Generico do medicamento tecta 40 mg /kg tincidibio)
Toxicity:
A dose of 40 mg/kg given intravenously caused fatal heart failure, renal failure and death.
Drug Interactions:
The effect of nitrous oxide on the CNS is complicated by interactions of nitrous oxide with other drugs.
Drugs which decrease metabolic oxygen consumption (such as diuretics) increase the incidence of respiratory depression in patients with induced by nitrous oxide.
Nitrous oxide and nitric should therefore be avoided when used with other drugs that cause respiratory depression, including diuretics.
When using nitrous oxide with other CNS depressants, the safety of nitrous oxide must be carefully monitored.
Nitrous oxide also interacts with noncompetitive amino acid receptor antagonists.
Nitrous oxide has been detected in the serum of patients receiving nitrous oxide for an extended period of time. Use nitrous oxide in patients receiving diuretics or other substances that decrease metabolic oxygen consumption can significantly increase the risk of respiratory depression.
Carcinogenesis, Mutagenesis, Impairment of Fertility
Carcinogenesis:
Nitrite has been shown to promote carcinogenesis. This may occur by causing a decrease in glutathione synthesis. Nitrite was shown to cause DNA mutations and damage in human liver cells (P<0.005) experiments conducted under the conditions of present study. Tumor cells from mice given a single 1 mg/kg intraperitoneal injection of nitrite exhibited an increase in chromosome aberrations and were more prominent in female mice. Tumor cell lines from Sprague-Dawley rats given a single 2 mg/kg intraperitoneal injection of tecta 40 mg generico nitrite (6 days after surgery) showed an increase in the frequency of mitotic activity on chromosome 21. In one experiment which mice were injected with nitrite (in the livers of mice) followed by 6 weeks of drinking tap water, nitrite was shown to cause a significant increase in both the number of cancers and size the tumors in mice. rats, nitrite (in the livers of rats) was shown to cause an increase in mammary cancer and an increase in prostate cancer.
Mutagenesis:
Nitrite has been shown to inhibit in vitro DNA synthesis the human colon cancer (Colp2-1) cell line.
Impairment of Fertility:
Nitrite has been shown to interfere with the reproductive system of animals. In a study conducted rats, nitrite and nitrite-nitrosamine were shown to interact with the human sperm DNA and cause a change in the number and quality of chromosomes.
Precautions:
It is generally recognized that nitrites are extremely corrosive. Therefore, a precaution is necessary in administering nitrite to patients. should be administered in a dose sufficient to produce Venlafaxine generic cost no reaction in adults under medical supervision. The use of nitrite in hospital setting is discouraged because of its corrosive action and because it is difficult to determine the amount of nitrite required for each dose.
Patients should be Buy atarax 25mg cautioned against the use of nitrous oxide for more than a short duration because of its potentially serious side effects.
Nausea and Vomiting
Nausea:
The mean duration of nausea and vomiting after nitrous oxides administration ranged from 1 to 5 hours.
Vomiting in patients receiving nitrous oxide usually occurred 5 to 20 minutes after the administration of nitrous oxide. vomiting usually subsided within 30 minutes.
Pregnancy:
Elimination of nitrous oxide is decreased in pregnant women. A number of complications have been reported after prolonged nitrous oxide administration to pregnant women.
Geriatrics:
Geriatric patients should be advised of the dangers associated with nitrous oxide use. It is estimated that nitrous oxide exposure is approximately one-half to three-fourths as hazardous the elderly to younger persons.
Dental Caries:
The effect of nitrous oxide on the oral health of elderly has not been defined. For this reason, nitrous oxide should not be administered by the elderly.
Liver Toxicity:
Nitrite has been shown to affect the liver of mice, dogs and rats. A number of Tecta 120 Pills 5mg $480 - $4 Per pill experimental animals have been treated with nitrite in an attempt to determine the effects on liver. One group of animals received a single 1 mg/kg intraperitoneal injection of nitrite (6 days after surgery). One group of animals received a single 2 mg/kg intraperitoneal injection of nitrite followed by 6 weeks of drinking tap water. The 2 mg/kg dose produced an immediate decrease in the hepatic level of glutathione (GSH). In the first experiment, GSH was measured in the blood after administration.
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